The non-slip mat is made of 100% silicone and are completely non-toxic and free of chemicals. You can wash them by mild soap or even using the autoclave, dishwasher. It is anti-microbial and can be used in areas which need to be sterile. This mat is completely adhesive free and highly non-slip secured suitable for wide range of applications. This mat protects the surface of tables or kitchen countertops, when you place hot cooking pans, pots, mugs and plates. It can be washed with mild detergent or with the help of an autoclave sterilize.